A novel hydrodynamic approach of dragreducing polymers to improve left ventricular hypertrophy and aortic remodeling in spontaneously hypertensive rats xinlu zhang,1, xu wang,2, feng hu,1 boda zhou,3 haibin chen,1 daogang zha,1 yili liu,1 yansong guo,4 lemin zheng,2 jiancheng xiu1 1department of cardiology, nanfang hospital, southern medical university, guangzhou, 2the institute of. From a matrix tablet with polyox wsr1105 nf and wsr303 nf 1. The swelling ratio of peo was approximately twice as that of hpmc in acidic and neutral testing media. Download latest karnataka state drug logistics and warehousing society tenders and documents, get live tender bidding support for karnataka state drug logistics and warehousing society tenders, online eprocurement karnataka state drug logistics and warehousing society tenders, gem registration services. Motivated by observations of the effects of dragreducing polymer additives on various aspects of blood flow, suspensions of fluidfilled elastic capsules in newtonian fluids and dilute solutions of high molecular weight dragreducing polymers are investigated during plane couette flow in a slit geometry. Peo hot melt extrudates for controlled drug delivery. Polyox for lighting industry hot melt glue distributor. All india tenders portal get email alerts and track all tenders from india that includes government tenders, corporate tenders, public tenders, procurement notices, global tenders and industry specific tenders. Polyox watersoluble resins, nf grade comply with the. Whether used for adhesives, ceramics, catalytic converters, consumer electronics, paper, photovoltaics, paints and coatings or batteries, products containing cellulosics help improve the daily lives of billions of people. When used in oral applications, polyox wsr systems do not show a strong ph response due to their nonionic nature.
Wsr301 wsr coagulant wsr303 wsr308 ucarfloc polymer 300 ucarfloc. Cn1691965b pharmaceutical composition for controlled. India tenders, public tenders, public notices, private. A simple model is presented to describe the crossstream distribution of capsules as a. Peg45m has a weight average molecular weight of 2,000,000 dalton.
Pharmaceutics free fulltext influence of high, disperse. Polyoxtm wsr environmental precautions do not discharge onto the ground or into water courses. Polyox wsr205 peg 14m polyox wsrn60k pegg 45m lub polyox wsrn750 peg 7m pl 209 379 b1 11 substancje nawilzajace, takze okreslane jako srodki utrzymujace wilgoc albo srodki zmiekczajace, mozna korzystnie stosowac w wynalazku. They hydrate rapidly to form a gel layer on the tablet surface. Srodki utrzymujace wilgoc, jak wielowodorotlenowe alkohole, np. Wsr n12k nf 1,000,000 400 800 m e d i u m s o l u b i l i t y. This product can be used in shaving products, body washes, liquid hand soaps, bar soaps and styling gels. Pair collisions of fluidfilled elastic capsules in shear. Polyox wsr n60k dow datasheet cosmetics ingredients. Wsr coagulant storm sewers wsr301 about 200 reduces turbulent frictional wsr303 drag by as much as 80%.
Pdf application of polyethylene oxide in hydrophilic matrix tablets. A particle sizecontrolling substance containing a drug, polyethylene oxide having a molecular weight of 2,000,000 or more and a particle sizecontrolling agent a substance having appropriate plasticizing properties and binding force for the polyethylene oxide wherein at least the particle sizecontrolling agent as specified above is uniformly dispersed in the polyethylene oxide. Polyox tm water soluble resins combining flexibility with. Characterization of compressibility and compactibility of.
While thermoelastic, polyox wsr polymers can also exhibit a thermoplastic behavior. Useful deposition enhancers are available from dow under their polyox brand. This versatility has made polyox wsr a popular choice for many industrial applications. Polyox wsr n3000 by dow chemical acts as an emollient, foam booster and slip agent. Polyox watersoluble resins in aqueous drag reduction and drift control application recommended grades use levels, ppm benefits firefighting wsr 30 5100 reduces turbulent frictional additives wsr 303 drag by as much as 80%. Suitable polyox includes polyox wsr coagulant, polyox wsr 301, polyox wsr 303, polyox wsr n 12k, polyox wsr n 60k, polyox wsr 1105, polyox wsr 205, and polyox wsr n 3000. Polyox water soluble resins are nonionic polymers that deliver sensory enhancement to a range of personal care products. Explore applications which can be enhanced by our products. Unlike other polymers, polyox wsr combines water and solvent solubility. Villanueva, a novel hydrodynamic approach to the treatment of coronary artery disease, european heart journal, volume 27, issue 19, october 2006, pages 23622369.
Strain energy function of red bloodcell membranes, biophys. The dynamics and pair collisions of fluidfilled elastic capsules during couette flow in newtonian fluids and dilute solutions of highmolecular weight dragreducing polymers are investigated via direct simulation. Polyox watersoluble resins nf in pharmaceutical applications. Polyox films demonstrated higher bioadhesion than hpc films because polyox hydrates faster, takes up more water and swell more than hpc. As there are few approaches reported that systematically investigate the influence of high disperse active. Distributor channel partner of polyox for lighting industry hot melt glue, polyox, polyox watersoluble resins and maplitho ss paper offered by shivananda marketing private limited, delhi. It improves tactile properties of water phase and overall aesthetics. Peo with a molecular weight of 100,000 sentry polyox wsr n10nf grade. Canadian patents database patent 2740342 summary thirdparty information liability. Some of the information on this web page has been provided by external sources. Hydroxyethyl cellulose and glycerol are considered to be safe in cases of intravasation or intraabdominal application. Application of polyethylene oxide in hydrophilic matrix tablets article pdf available in pharma times 453. Polyox wsr n60k by dow acts as a slip agent and foam booster. Hydrophilic matrix tablet technology has been widely used for extended release oral applications.
In bar soaps, the addition of polyox wsr n60k provides excellent slip properties and leaves skin with a smooth and conditioned afterfeel. A long chain poly ethylene oxide, polyox is available in a wide range of molecular weights making it an excellent choice for a formulator trying to tailor a specific end viscosity. In order to cope with the increasing number of multimorbid patients due to demographic changes, individualized polypill solutions must be developed. Used in shaving products, body washes, liquid hand soaps, bar soaps and styling gels.
Repeated dose toxicity based on available data, repeated exposures are not anticipated to cause significant adverse effects. Wsr coagulant storm sewers wsr 301 about 200 reduces turbulent frictional wsr 303 drag by as much as 80%. Characterization of compressibility and compactibility of polyethylene oxide polymers for modified release application by compaction simulator l ibo y ang, g opi v enkatesh. Peo with a narrow molecular weight distribution hereafter referred to as peo 0.
Safety data sheet polyoxtm wsr 1 identification of the substancepreparation and companyundertaking product name polyoxtm wsr synonyms, trade names 301 amerchol, n12k amerchol, n60k amerchol, n10, n80, n3000, n750, application lubricant supplier univar ltd 46 peckover street bradford. Polyox polyethylene oxide multifunctional polymer in novel drug. Excipient properties affecting the mechanical performance. The data in figure 7 show release profiles collected at different ph values for a theophylline matrix system. Polyox wsr205 peg 14m polyox wsrn60k pegg 45m lub polyox wsrn750 peg 7m pl 209 379 b1 11. Polyox polyethylene oxide multifunctional polymer in novel. It improves overall aesthetics and tactile properties of water phase. Polyox wsr n750 by dow is a watersoluble foam booster and slip agent. As a result of its wide ranging compatibility, it is readily used in a variety. The government of canada is not responsible for the accuracy, reliability or currency of the information supplied by external sources. Polyox polyethylene oxide multifunctional polymer in.
Pdf application of polyethylene oxide in hydrophilic matrix. The viscoelastic properties enable reduction of spattering and misting. All india tenders portal get email alerts and track all tenders from india that includes government tenders, corporate tenders, public tenders, procurement. Composition for providing a film on keratin fibres the. Polyox wsr n60k improves the foam quality and feel in skin and hair cleansing formulations, providing cues which reinforce the perception of moisturization and softness. Polyox watersoluble resins are very hydrophilic polymers. They form flexible, and tough film which are resistant to oils and greases. Polyethylene oxide peo is a unique hydrophilic polymer that has been successfully used in many. Hydroxyethyl cellulose an overview sciencedirect topics.
These high molecular weight, nonionic water soluble polyethylene oxide polymers increase lubricity, binding, and water retention, and can be used in a wide spectrum of applications. Polyox wsr n80 by dow acts as a lubricant slip agent and foam booster. Recent studies have demonstrated that an anionic polyacrylamide separan, union carbide corp. Application of polyethylene oxide in hydrophilic matrix. Polyox wsr n60k is a water soluble peg45m with a relatively high molecular weight. A novel hydrodynamic approach to the treatment of coronary artery disease.
Hemodynamic effects of a polyethylene oxide drag reducing polymer, polyox wsr n60k. Polyox watersoluble resins are high molecular weight water soluble polymers. Coco amido propyl betaine paktradeinfo global import. Polyethylene oxide peo is a unique hydrophilic polymer that has been successfully. Full text a novel hydrodynamic approach of dragreducing. Polyox wsr301 foaming agent by dow technical datasheet. One promising tool is fused layer modeling flm of dosage forms with patientspecific dose combinations and release individualization. Ksadl procurement of polyox wsr n 60k peg 45m 1 polyox wsr n 60k peg 45m, due date. In a cream, lotion, gel or stick the product will go a long way toward making your products glide on smoothly. Capsule membranes are modeled using either a neohookean constitutive model or a model introduced by skalak et al. Polyox wsr301 by dow acts as a foam booster and slip agent.
Ethyl cellulose for use in accordance with the present invention can include those sold under the trademark ethocel dow chemical co. It is widely used as binder, lubricant, thickener and. Polyox wsr has been used for over 50 years for its unique properties. Business to business b2b trade directory and catalog. They are available in molecular weight ranges between 100. Karnataka state drug logistics and warehousing society.
Spill clean up methods avoid generation and spreading of dust. The dow chemical company encourages and expects you to read. For reasons of comparison, also the dsc thermograms of the respective physical powder mixtures dashed curves as well as of the pure drug and pure peo powders as received. Conclusions polyox watersoluble resins nf are highly. Procurement of polyox wsr n 60k peg 45m 1 polyox w tender. Polyox can be used as alternative to hpmc as tablet binder in direct compression. Figure 3sheckel plots of sieved polyox wsr of different molecular weights 0. It is based on a long chain nonionic polyethylene oxide polymer. These results indicate that dragreducing polymers may represent a novel class of potassiumsparing diuretic and natriuretic compounds. Download latest karnataka state drug logistics and warehousing society tenders and documents, get live tender bidding support for karnataka state drug logistics and warehousing society tenders, online eprocurement karnataka state drug logistics and warehousing society tenders, gem. Guest users can see 10 rows of a randomly selected item. Characterization of compressibility and compactibility. N60k 301 coag 303 308 dupont polyox wsr product line.
At this infusion rate, only hypertonic concentrations of mannitol 20% induced a similar effect. Polyox wsr 60k is a polyethylene oxide with a viscosity of 2000 4000 cp in a 2% aqueous solution. Please sign in to see data specific to your search. Depletion layer formation in suspensions of elastic. Polyox wsr n60k is used in shaving products, body washes, liquid hand soaps, bar soaps and styling gels. Aug 18, 2016 useful deposition enhancers are available from dow under their polyox brand. Join dupont specialty solutions team at the european coating. Us6048547a process for manufacturing solid compositions.
Polyox wsr n60k by dow chemical home and personal care. Coco amido propyl betaine, over 6,000,000 trade data importers and exporters. Polyox wsr301, polyox wsr303, polyox wsr n12k, polyox wsr n60k, polyox wsr1105, polyox wsr205, and polyox wsr n3000. Although polyox watersoluble resins are completely water soluble in typically 0. Lower molecular weight polyox are widely used for immediate drug release based. Jp2015534561a dosage form containing terbutaline sulfate. Polyox watersoluble resins in aqueous drag reduction and drift control application recommended grades use levels, ppm benefits firefighting wsr30 5100 reduces turbulent frictional additives wsr303 drag by as much as 80%. Excipient properties affecting the mechanical performance of abuse deterrent formulations development and regulation of abusedeterrent opioid medications public meeting. As expected, the release rate does not vary as a function of ph. Separan, but not polyox, produced a modest increase in blood pressure. It is widely used as binder, lubricant, thickener and water retention aid. Polyox watersoluble resins, natural and synthetic resins. Read examination of drug solubility, polymer types, hydrodynamics and loading dose on drug release behavior from a triplelayer asymmetric configuration delivery system, international journal of pharmaceutics on deepdyve, the largest online rental service for scholarly research with thousands of academic publications available at your fingertips. Wsr n60k 2,000,000 2,000 4,000 wsr301 4,000,000 1,650 5,500 wsr303 7,000,000 7,500 10,000 moisture content moisture content of the polyox samples was deter mined by using a loss on drying lod method in an oven heraeus, uk at 105.
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